Pathogens are a critical barrier to successful cannabis cultivation. While multiple pathogens impact cannabis, Hop Latent Viroid (HLVd) represents one of the most damaging. Because this pathogen can initially present asymptomatically and spread undetected through a facility, HLVd can destroy an entire harvest(s), resulting in catastrophic economic consequences for a cultivator. With confirmed cases of HLVd infected cannabis throughout the United States and internationally, effective management of this pathogen is an obligatory consideration to stay competitive in the cannabis industry. Steps can be taken to prevent HLVd damage. However, these actions require a basic understanding of viroid biology/life cycle and a solid grasp of effective testing procedures and schedules. In this talk Dr. Tassa Saldi will provide a laymen overview of viroid biology including how viroids differ from more familiar pathogens such as viruses, bacteria and fungus. Preliminary data addressing many critical questions will be presented including: the frequency of seed transmission and variation of viroid load throughout a cannabis plant. Routes of HLVd transmission will also be discussed as well as effective and ineffective chemicals for removing viroid contamination. Because no effective cure for HLVd currently exists, rigorous preventative testing is the best defense. Dr. Saldi will give an overview of the various HLVd testing options and what a cultivator should look for when choosing a testing lab. Finally, recommendations regarding sample collection, ideal HLVd testing schedules and how to mitigate losses from HLVd when it is found in a facility will be reviewed.